MSc/PhD Program
Bassel Makhouly
First Name:
Bassel

Last Name:
Makhouly

Country:
Israel

 

 

 

 



Bassel Makhouly

EDUCATION

College / University:
University of Osnabrück, University of Göttingen

Highest Degree:
Diplom (Biology), University of Göttingen

Major Subjects:
Molecular genetics (major), immunology, organic chemistry, microbiology

Projects / Research:
Diploma thesis "Expression and Regulation of Estradiol-Receptors Type a and b in Endocrine Organs of the Rat"; examination of regulation of the expression of both ER subtypes in hypothalamic areas relevant for the feedback action of estrogen on hormone secretion; to address this issue: development of an animal model and the RT-Triplex-PCR method for ERa , ERß and L7. With this work I was able to show an autoregulation of ERa and ERb expression by E2, depending on the nucleus investigated, as an agonist or antagonist

SCIENTIFIC INTERESTS AND GOALS:

Ph.D. project at the University of Göttingen, Dept of Clinical and Experimental Endocrinology ( Prof. Dr. W. Wuttke, Prof. Dr. H. Jarry). Focus on neuroendocrinology, particularly on the process of aging of the reproductive functions in the central nervous system of the female rat. Methods: in situ hybridization, immunocytochemistry, quantitative RT-PCR. Participation in an additional project: cloning and localizing the gene IL-1 beta from the marmoset monkey (Callithrix jacchus).