MSc/PhD Program
Raunak Sinha
First Name:
Raunak

Last Name:
Sinha

Country:
India

 

 



Raunak Sinha

EDUCATION

College / University:
2005 - 2006: Tata Institute of Fundamental Research India
2002 - 2005: Presidency College / University of Calcutta, India

Highest Degree:
B.Sc. (Honours) in Physiology

Major Subjects:
Physiology, Molecular Biology

Lab Experience:
Histology, experimental physiology (nerve muscle recordings, perfusion experiments on cardiac and smooth muscle), work physiology (measurement of physical fitness indices), recombinant DNA technology ( DNA isolation, PCR, cloning, transformation, site-directed mutagenesis), DNA/protein gel electrophoresis, immunoprecipitation, RNA-protein cross-linking studies, RT-PCR, immunohistochemistry, protein expression and purification studies, affinity chromatography.

Projects / Research:
Jul 05 - Jun 06: Dept. of Biological Sciences, Tata Institute of Fundamental Research, Mumbai , India : Identifying a putative role of the molecule ‘Translin’ in mRNA processing, subcellular localization and translational regulation in Drosophila Melanogaster.
Jun - Jul 05: Studying the pharmacological properties of  Analgesic drugs (topical analgesics) at Glaxosmithkline, India .
Nov 04: Evaluating physiological parameters (cardiovascular, anthropometric, haematological, socio-economic, and nutritional) in a field survey of tribal inhabitants in the northeastern part of India .

Scholarships:
2006 - 2007: Stipend International Max Planck Research School, Germany
Jul 05 - Jun 06: Stipend Junior Research Scholar, Tata Institute of Fundamental Research, India
Jun - Jul 05: Stipend Research trainee, GlaxoSmithkline, India

SCIENTIFIC INTERESTS AND GOALS:
My scientific goal is to understand neuronal plasticity at the molecular level. Long-lasting forms of synaptic plasticity in mammalian brain require local mRNA translation and hence protein synthesis from pre-existing mRNA at the synapse. I am interested in understanding the regulatory mechanisms that facilitate subcellular localization of mRNA, their storage at the synapse and gene expression which are essential for synaptogenesis, axon navigation and memory formation. I am keen on studying how the local repertoire of translational factors enable the synapse to control synaptic strength independent of the cell soma and whether there lies any difference in the biochemical mechanisms governing translation at the synapse.