MSc/PhD Program
Melanie Nuesch Germano
First Name:
Melanie

Last Name:
Nuesch Germano

Country:
Uruguay

 



Melanie Nuesch Germano

EDUCATION

College / University:
Universidad de la República

Highest Degree:
B.Sc.

Major Subjects:
Human Biology, Minor: Neuroscience

Lab Experience:
Computational: Windows, Linux and Mac (Bash shell) advanced user; human genomic data analysis and big data handling (for clinical and evolutionary/population genomics purposes); statistical software programming (especially MATLAB, R and Plink); gene panel designing; molecular and genomic data bases usage
Wet Lab: Western Blot; basic laboratory skills; dissection and suture

Projects / Research:
Jun 2016 – Jun 2017: Internship at Institut Pasteur de Montevideo, Uruguay, Bioinformatics Unit (Spangenberg, Raggio, Barbeito. Bachelor's thesis: "Study of 41 genetic markers of late onset Alzheimer's disease risk in 28 populations of the world."
Aug 2015 – Jun 2016: Internship at Institut Pasteur de Montevideo, Bioinformatics Unit (Spangenberg, Raggio). Gene panel design for epilepsy and Alzheimer’s disease. Learning bioinformatical basic skills
Mar – Jul 2015: Internship at Institut Pasteur de Montevideo, Neurodegeneration Lab (Barbeito). Western blotting to compare KPRP levels in cerebrospinal fluid samples of transgenic SOD1 mice (ALS model) and control mice
2012 – 2013: Internship at Clemente Estable Institute (IIBCE), Computational Neuroscience Lab (Caputi), Montevideo. “Does Gymnotus carapo show a mixed type neuro-myogenic organ?”

Scholarships:
2017 – 2018: Stipend by the International Max Planck Research School
2012: "PAIE" grant of CSIC (Sectorial Commission of Scientific Research of the University of the Republic, Uruguay), approved "with distinction"; project: "Does Gymnotus carapo show a mixed type neuro-myogenic organ?"

SCIENTIFIC INTERESTS AND GOALS:

I am interested in neurogenetics and epigenetics, particularly their role in pathology (for instance, in neurodegeneration). I think modern molecular biology is a neat tool for modelling the complexity and dynamism of both normal physiology and pathology of the brain, and holds the key to new theories, diagnoses, and therapies. Especially in psychopathologies, advancement is paramount, since some of them are part of a complex continuum where they can overlap.